Jump to content

Motile sperm domain containing 2

From Wikipedia, the free encyclopedia
MOSPD2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMOSPD2, Motile sperm domain containing 2
External IDsMGI: 1924013; HomoloGene: 22125; GeneCards: MOSPD2; OMA:MOSPD2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001177475
NM_152581
NM_001330241

NM_001290523
NM_001290524
NM_029730

RefSeq (protein)

NP_001170946
NP_001317170
NP_689794

NP_001277452
NP_001277453
NP_084006

Location (UCSC)Chr X: 14.87 – 14.92 MbChr X: 163.72 – 163.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Motile sperm domain containing 2 is a protein that in humans is encoded by the MOSPD2 gene.[5] It is an endoplasmic reticulum–resident protein involved in membrane contact site formation.[6] Its domain homologous to Major Sperm Protein (MSP domain) is very similar to VAPA/VAPB, so it has been described as the third human member of the VAP protein family.

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130150Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000061778Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Motile sperm domain containing 2".
  6. ^ Di Mattia T, Wilhelm LP, Ikhlef S, Wendling C, Spehner D, Nominé Y, Giordano F, Mathelin C, Drin G, Tomasetto C, Alpy F (June 2018). "Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites". EMBO Reports. 19 (7): e45453. doi:10.15252/embr.201745453. PMC 6030701. PMID 29858488.

Further reading

[edit]
[edit]
  • PDBe-KB provides an overview of all the structure information available in the PDB for Mouse Motile sperm domain-containing protein 2